1y5x

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Revision as of 12:24, 5 January 2013

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Template:STRUCTURE 1y5x

tRNA-guanine Transglycosylase (TGT) in complex with 6-Amino-4-[2-(4-methoxyphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Template:ABSTRACT PUBMED 17524419

About this Structure

1y5x is a 2 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

• Stengl B, Meyer EA, Heine A, Brenk R, Diederich F, Klebe G. Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding. J Mol Biol. 2007 Jul 13;370(3):492-511. Epub 2007 Apr 12. PMID:17524419 doi:10.1016/j.jmb.2007.04.008