1x2r

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[[Image:1x2r.png|left|200px]]
[[Image:1x2r.png|left|200px]]
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{{STRUCTURE_1x2r| PDB=1x2r | SCENE= }}
{{STRUCTURE_1x2r| PDB=1x2r | SCENE= }}
===Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2===
===Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2===
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{{ABSTRACT_PUBMED_16507366}}
{{ABSTRACT_PUBMED_16507366}}
==About this Structure==
==About this Structure==
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1X2R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X2R OCA].
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[[1x2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X2R OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16507366</ref><references group="xtra"/>
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<ref group="xtra">PMID:016507366</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Kang, M I.]]
[[Category: Kang, M I.]]
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[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:15:43 2009''
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Revision as of 13:14, 5 January 2013

Image:1x2r.png

Template:STRUCTURE 1x2r

Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2

Template:ABSTRACT PUBMED 16507366

About this Structure

1x2r is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M. Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Mol Cell. 2006 Mar 3;21(5):689-700. PMID:16507366 doi:10.1016/j.molcel.2006.01.013

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