1wok

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Image:1wok.png

Template:STRUCTURE 1wok

Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor

Template:ABSTRACT PUBMED 15733846

About this Structure

1wok is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Iwashita A, Hattori K, Yamamoto H, Ishida J, Kido Y, Kamijo K, Murano K, Miyake H, Kinoshita T, Warizaya M, Ohkubo M, Matsuoka N, Mutoh S. Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors. FEBS Lett. 2005 Feb 28;579(6):1389-93. PMID:15733846 doi:10.1016/j.febslet.2005.01.036

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OCA

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