2c6e
From Proteopedia
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[[Image:2c6e.png|left|200px]] | [[Image:2c6e.png|left|200px]] | ||
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{{STRUCTURE_2c6e| PDB=2c6e | SCENE= }} | {{STRUCTURE_2c6e| PDB=2c6e | SCENE= }} | ||
===AURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH A 5-AMINOPYRIMIDINYL QUINAZOLINE INHIBITOR=== | ===AURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH A 5-AMINOPYRIMIDINYL QUINAZOLINE INHIBITOR=== | ||
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{{ABSTRACT_PUBMED_16337122}} | {{ABSTRACT_PUBMED_16337122}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2c6e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C6E OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016337122</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
| - | [[Category: Nucleotide-binding]] | + | [[Category: Nucleotide- binding]] |
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Transferase | + | [[Category: Transferase-inhibitor complex]] |
| - | + | [[Category: Transferase/inhibitor]] | |
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Revision as of 09:19, 6 January 2013
AURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH A 5-AMINOPYRIMIDINYL QUINAZOLINE INHIBITOR
Template:ABSTRACT PUBMED 16337122
About this Structure
2c6e is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Heron NM, Anderson M, Blowers DP, Breed J, Eden JM, Green S, Hill GB, Johnson T, Jung FH, McMiken HH, Mortlock AA, Pannifer AD, Pauptit RA, Pink J, Roberts NJ, Rowsell S. SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1320-3. Epub 2005 Dec 5. PMID:16337122 doi:10.1016/j.bmcl.2005.11.053
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Anderson, M. | Breed, J. | Mcmiken, H H.J. | Pannifer, A D. | Pauptit, R A. | Rowsell, S. | Atp-binding | Aurora | Cancer | Cell cycle | Kinase | Nucleotide- binding | Phosphorylation | Serine/threonine-protein kinase | Transferase | Transferase-inhibitor complex | Transferase/inhibitor
