2aox
From Proteopedia
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[[Image:2aox.png|left|200px]] | [[Image:2aox.png|left|200px]] | ||
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{{STRUCTURE_2aox| PDB=2aox | SCENE= }} | {{STRUCTURE_2aox| PDB=2aox | SCENE= }} | ||
===Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine=== | ===Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine=== | ||
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{{ABSTRACT_PUBMED_16168438}} | {{ABSTRACT_PUBMED_16168438}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Asthma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605238 605238]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2aox]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOX OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016168438</ref><references group="xtra"/> |
[[Category: Histamine N-methyltransferase]] | [[Category: Histamine N-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Classic methyltransferase fold]] | [[Category: Classic methyltransferase fold]] | ||
[[Category: Protein-drug complex]] | [[Category: Protein-drug complex]] | ||
- | + | [[Category: Transferase]] | |
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Revision as of 09:52, 6 January 2013
Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine
Template:ABSTRACT PUBMED 16168438
About this Structure
2aox is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Horton JR, Sawada K, Nishibori M, Cheng X. Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:16168438 doi:10.1016/j.jmb.2005.08.040