2aox

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{{Seed}}
 
[[Image:2aox.png|left|200px]]
[[Image:2aox.png|left|200px]]
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{{STRUCTURE_2aox| PDB=2aox | SCENE= }}
{{STRUCTURE_2aox| PDB=2aox | SCENE= }}
===Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine===
===Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine===
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{{ABSTRACT_PUBMED_16168438}}
{{ABSTRACT_PUBMED_16168438}}
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==Disease==
 
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Known disease associated with this structure: Asthma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605238 605238]]
 
==About this Structure==
==About this Structure==
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2AOX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOX OCA].
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[[2aox]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOX OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16168438</ref><references group="xtra"/>
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<ref group="xtra">PMID:016168438</ref><references group="xtra"/>
[[Category: Histamine N-methyltransferase]]
[[Category: Histamine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Classic methyltransferase fold]]
[[Category: Classic methyltransferase fold]]
[[Category: Protein-drug complex]]
[[Category: Protein-drug complex]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:24:23 2009''
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Revision as of 09:52, 6 January 2013

Template:STRUCTURE 2aox

Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine

Template:ABSTRACT PUBMED 16168438

About this Structure

2aox is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Horton JR, Sawada K, Nishibori M, Cheng X. Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:16168438 doi:10.1016/j.jmb.2005.08.040

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