2ada

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Revision as of 10:06, 6 January 2013

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spinqualitylabelsall models PDB ID 2ada Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2ada, resolution 2.40Å ()
Ligands:	,
Activity:	Adenosine deaminase, with EC number 3.5.4.4
Structural annotation: Resources: CATH : 2Ada000 InterPro : Ipr001365, Ipr006650, Ipr006330 Pfam : PF00962 SCOP : d2ada__ UniProt : P03958
Functional annotation: Cellular component: cytoplasm Biological process: purine nucleotide metabolic process immune response purine ribonucleoside monophosphate biosynthetic process nucleotide metabolic process Molecular function: metal ion binding hydrolase activity deaminase activity adenosine deaminase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS

Template:ABSTRACT PUBMED 1925539

About this Structure

2ada is a 1 chain structure with sequence from Mus musculus. This structure supersedes the now removed PDB entry 1ada. Full crystallographic information is available from OCA.

Reference

• Wilson DK, Rudolph FB, Quiocho FA. Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations. Science. 1991 May 31;252(5010):1278-84. PMID:1925539