1v0k
From Proteopedia
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==Overview== | ==Overview== | ||
| - | The atomic resolution structures of xylobiose-derived isofagomine and | + | The atomic resolution structures of xylobiose-derived isofagomine and xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the enzyme's catalytic machinery upon binding. |
==About this Structure== | ==About this Structure== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Streptomyces lividans]] | [[Category: Streptomyces lividans]] | ||
| - | [[Category: Davies, G | + | [[Category: Davies, G J.]] |
| - | [[Category: Gloster, T | + | [[Category: Gloster, T M.]] |
[[Category: Roberts, S.]] | [[Category: Roberts, S.]] | ||
| - | [[Category: Tarling, C | + | [[Category: Tarling, C A.]] |
| - | [[Category: Williams, S | + | [[Category: Williams, S J.]] |
| - | [[Category: Withers, J | + | [[Category: Withers, J Wicki S G.]] |
[[Category: deoxynojirimycin]] | [[Category: deoxynojirimycin]] | ||
[[Category: glycoside hydrolase family 10]] | [[Category: glycoside hydrolase family 10]] | ||
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[[Category: xylanase]] | [[Category: xylanase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:30:18 2008'' |
Revision as of 13:30, 21 February 2008
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 5.8
Overview
The atomic resolution structures of xylobiose-derived isofagomine and xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the enzyme's catalytic machinery upon binding.
About this Structure
1V0K is a Single protein structure of sequence from Streptomyces lividans. Active as Endo-1,4-beta-xylanase, with EC number 3.2.1.8 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A., Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ, Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887
Page seeded by OCA on Thu Feb 21 15:30:18 2008
