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2c6d

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Revision as of 10:19, 6 January 2013

Image:2c6d.png

Template:STRUCTURE 2c6d

AURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH ADPNP

Template:ABSTRACT PUBMED 16337122

About this Structure

2c6d is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Heron NM, Anderson M, Blowers DP, Breed J, Eden JM, Green S, Hill GB, Johnson T, Jung FH, McMiken HH, Mortlock AA, Pannifer AD, Pauptit RA, Pink J, Roberts NJ, Rowsell S. SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1320-3. Epub 2005 Dec 5. PMID:16337122 doi:10.1016/j.bmcl.2005.11.053

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OCA

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