2auh
From Proteopedia
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===Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase=== | ===Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2auh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUH OCA]. | |
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| + | ==See Also== | ||
| + | *[[Insulin receptor|Insulin receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016246733</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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[[Category: Hubbard, S R.]] | [[Category: Hubbard, S R.]] | ||
[[Category: Bps region]] | [[Category: Bps region]] | ||
| - | [[Category: Transferase | + | [[Category: Transferase-signaling protein complex]] |
[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:39:19 2009'' | ||
Revision as of 10:59, 6 January 2013
Contents |
Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase
Template:ABSTRACT PUBMED 16246733
About this Structure
2auh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR. Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. Mol Cell. 2005 Oct 28;20(2):325-33. PMID:16246733 doi:10.1016/j.molcel.2005.09.001
