This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2aot
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2aot.png|left|200px]] | [[Image:2aot.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2aot", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2aot| PDB=2aot | SCENE= }} | {{STRUCTURE_2aot| PDB=2aot | SCENE= }} | ||
===Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine=== | ===Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16168438}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16168438 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16168438}} | {{ABSTRACT_PUBMED_16168438}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Asthma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605238 605238]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2aot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOT OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016168438</ref><references group="xtra"/> |
[[Category: Histamine N-methyltransferase]] | [[Category: Histamine N-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 35: | Line 20: | ||
[[Category: Classic methyltransferase fold]] | [[Category: Classic methyltransferase fold]] | ||
[[Category: Protein-drug complex]] | [[Category: Protein-drug complex]] | ||
| - | + | [[Category: Transferase]] | |
| - | + | ||
Revision as of 11:53, 6 January 2013
Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine
Template:ABSTRACT PUBMED 16168438
About this Structure
2aot is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Horton JR, Sawada K, Nishibori M, Cheng X. Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:16168438 doi:10.1016/j.jmb.2005.08.040
