2abj

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[[Image:2abj.png|left|200px]]
[[Image:2abj.png|left|200px]]
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{{STRUCTURE_2abj| PDB=2abj | SCENE= }}
{{STRUCTURE_2abj| PDB=2abj | SCENE= }}
===Crystal structure of human branched chain amino acid transaminase in a complex with an inhibitor, C16H10N2O4F3SCl, and pyridoxal 5' phosphate.===
===Crystal structure of human branched chain amino acid transaminase in a complex with an inhibitor, C16H10N2O4F3SCl, and pyridoxal 5' phosphate.===
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{{ABSTRACT_PUBMED_16143519}}
{{ABSTRACT_PUBMED_16143519}}
==About this Structure==
==About this Structure==
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2ABJ is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ABJ OCA].
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[[2abj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ABJ OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16143519</ref><references group="xtra"/>
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<ref group="xtra">PMID:016143519</ref><references group="xtra"/>
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Plp-lys220 schiff base]]
[[Category: Plp-lys220 schiff base]]
[[Category: Pyridoxal-phosphate-dependent aminotransferase]]
[[Category: Pyridoxal-phosphate-dependent aminotransferase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:26:17 2009''
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Revision as of 12:00, 6 January 2013

Template:STRUCTURE 2abj

Crystal structure of human branched chain amino acid transaminase in a complex with an inhibitor, C16H10N2O4F3SCl, and pyridoxal 5' phosphate.

Template:ABSTRACT PUBMED 16143519

About this Structure

2abj is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hu LY, Boxer PA, Kesten SR, Lei HJ, Wustrow DJ, Moreland DW, Zhang L, Ahn K, Ryder TR, Liu X, Rubin JR, Fahnoe K, Carroll RT, Dutta S, Fahnoe DC, Probert AW, Roof RL, Rafferty MF, Kostlan CR, Scholten JD, Hood M, Ren XD, Schielke GP, Su TZ, Taylor CP, Mistry A, McConnell P, Hasemann C, Ohren J. The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6. PMID:16143519 doi:10.1016/j.bmcl.2005.07.058

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