2ae2

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Revision as of 12:06, 6 January 2013

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Template:STRUCTURE 2ae2

TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE

Template:ABSTRACT PUBMED 10387002

About this Structure

2ae2 is a 2 chain structure with sequence from Datura stramonium. Full crystallographic information is available from OCA.

Reference

• Yamashita A, Kato H, Wakatsuki S, Tomizaki T, Nakatsu T, Nakajima K, Hashimoto T, Yamada Y, Oda J. Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry. 1999 Jun 15;38(24):7630-7. PMID:10387002 doi:10.1021/bi9825044
• Tanaka M, Bateman R, Rauh D, Vaisberg E, Ramachandani S, Zhang C, Hansen KC, Burlingame AL, Trautman JK, Shokat KM, Adams CL. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol. 2005 May;3(5):e128. Epub 2005 Apr 5. PMID:15799708 doi:10.1371/journal.pbio.0030128