2o5d
From Proteopedia
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===Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study=== | ===Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study=== | ||
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{{ABSTRACT_PUBMED_17276060}} | {{ABSTRACT_PUBMED_17276060}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2o5d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5D OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017276060</ref><references group="xtra"/> |
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Rdrp]] | [[Category: Rdrp]] | ||
[[Category: Structure-based drug design]] | [[Category: Structure-based drug design]] | ||
| + | [[Category: Viral protein]] | ||
[[Category: Viral rna-directed rna polymerase]] | [[Category: Viral rna-directed rna polymerase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:06:27 2009'' | ||
Revision as of 10:39, 7 January 2013
Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study
Template:ABSTRACT PUBMED 17276060
About this Structure
2o5d is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Yan S, Appleby T, Larson G, Wu JZ, Hamatake RK, Hong Z, Yao N. Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1991-5. Epub 2007 Jan 19. PMID:17276060 doi:10.1016/j.bmcl.2007.01.024
