2o5d

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Revision as of 10:39, 7 January 2013

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Template:STRUCTURE 2o5d

Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study

Template:ABSTRACT PUBMED 17276060

About this Structure

2o5d is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

• Yan S, Appleby T, Larson G, Wu JZ, Hamatake RK, Hong Z, Yao N. Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1991-5. Epub 2007 Jan 19. PMID:17276060 doi:10.1016/j.bmcl.2007.01.024