2hs2
From Proteopedia
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[[Image:2hs2.png|left|200px]] | [[Image:2hs2.png|left|200px]] | ||
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{{STRUCTURE_2hs2| PDB=2hs2 | SCENE= }} | {{STRUCTURE_2hs2| PDB=2hs2 | SCENE= }} | ||
===Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)=== | ===Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)=== | ||
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{{ABSTRACT_PUBMED_16962136}} | {{ABSTRACT_PUBMED_16962136}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2hs2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS2 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016962136</ref><references group="xtra"/> |
| + | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Kovalevsky, A Y.]] | [[Category: Kovalevsky, A Y.]] | ||
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[[Category: Weber, I T.]] | [[Category: Weber, I T.]] | ||
[[Category: Aspartic protease active site surface binding site]] | [[Category: Aspartic protease active site surface binding site]] | ||
| - | + | [[Category: Hydrolase]] | |
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Revision as of 10:44, 7 January 2013
Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)
Template:ABSTRACT PUBMED 16962136
About this Structure
2hs2 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007
