2hs2

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Revision as of 10:44, 7 January 2013

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Template:STRUCTURE 2hs2

Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)

Template:ABSTRACT PUBMED 16962136

About this Structure

2hs2 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

• Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007