2opm

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[[Image:2opm.png|left|200px]]
[[Image:2opm.png|left|200px]]
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{{STRUCTURE_2opm| PDB=2opm | SCENE= }}
{{STRUCTURE_2opm| PDB=2opm | SCENE= }}
===Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461===
===Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461===
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{{ABSTRACT_PUBMED_19309137}}
{{ABSTRACT_PUBMED_19309137}}
==About this Structure==
==About this Structure==
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2OPM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPM OCA].
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[[2opm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPM OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19309137</ref><references group="xtra"/>
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<ref group="xtra">PMID:019309137</ref><references group="xtra"/>
[[Category: Geranyltranstransferase]]
[[Category: Geranyltranstransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein-bisphosphonate complex]]
[[Category: Protein-bisphosphonate complex]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:25:08 2009''
 

Revision as of 10:57, 7 January 2013

Template:STRUCTURE 2opm

Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461

Template:ABSTRACT PUBMED 19309137

About this Structure

2opm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, Chang TK, Lin FY, Van Beek E, Papapoulos S, Wang AH, Kubo T, Ochi M, Mukkamala D, Oldfield E. Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. J Am Chem Soc. 2009 Apr 15;131(14):5153-62. PMID:19309137 doi:10.1021/ja808285e

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