2gj8

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Template:STRUCTURE 2gj8

Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and K+

Template:ABSTRACT PUBMED 16763562

About this Structure

2gj8 is a 4 chain structure with sequence from Escherichia coli bl21(de3). Full crystallographic information is available from OCA.

Reference

  • Scrima A, Wittinghofer A. Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element. EMBO J. 2006 Jun 21;25(12):2940-51. Epub 2006 Jun 8. PMID:16763562
  • Gasper R, Meyer S, Gotthardt K, Sirajuddin M, Wittinghofer A. It takes two to tango: regulation of G proteins by dimerization. Nat Rev Mol Cell Biol. 2009 Jun;10(6):423-9. Epub 2009 May 8. PMID:19424291 doi:nrm2689
  • Chappie JS, Acharya S, Leonard M, Schmid SL, Dyda F. G domain dimerization controls dynamin's assembly-stimulated GTPase activity. Nature. 2010 May 27;465(7297):435-40. Epub 2010 Apr 28. PMID:20428113 doi:10.1038/nature09032

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