2opb
From Proteopedia
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[[Image:2opb.png|left|200px]] | [[Image:2opb.png|left|200px]] | ||
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{{STRUCTURE_2opb| PDB=2opb | SCENE= }} | {{STRUCTURE_2opb| PDB=2opb | SCENE= }} | ||
===Structure of K57A hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoHcy=== | ===Structure of K57A hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoHcy=== | ||
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{{ABSTRACT_PUBMED_17845018}} | {{ABSTRACT_PUBMED_17845018}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2opb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPB OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017845018</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylethanolamine N-methyltransferase]] | [[Category: Phenylethanolamine N-methyltransferase]] | ||
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[[Category: Martin, J L.]] | [[Category: Martin, J L.]] | ||
[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
- | + | [[Category: Transferase]] | |
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Revision as of 11:10, 7 January 2013
Structure of K57A hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoHcy
Template:ABSTRACT PUBMED 17845018
About this Structure
2opb is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385