2opb

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[[Image:2opb.png|left|200px]]
[[Image:2opb.png|left|200px]]
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{{STRUCTURE_2opb| PDB=2opb | SCENE= }}
{{STRUCTURE_2opb| PDB=2opb | SCENE= }}
===Structure of K57A hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoHcy===
===Structure of K57A hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoHcy===
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{{ABSTRACT_PUBMED_17845018}}
{{ABSTRACT_PUBMED_17845018}}
==About this Structure==
==About this Structure==
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2OPB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPB OCA].
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[[2opb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPB OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:17845018</ref><references group="xtra"/>
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<ref group="xtra">PMID:017845018</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]
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[[Category: Martin, J L.]]
[[Category: Martin, J L.]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:36:18 2009''
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Revision as of 11:10, 7 January 2013

Template:STRUCTURE 2opb

Structure of K57A hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoHcy

Template:ABSTRACT PUBMED 17845018

About this Structure

2opb is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385

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