2gu8

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[[Image:2gu8.png|left|200px]]
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{{STRUCTURE_2gu8| PDB=2gu8 | SCENE= }}
{{STRUCTURE_2gu8| PDB=2gu8 | SCENE= }}
===Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies===
===Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies===
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{{ABSTRACT_PUBMED_16765046}}
{{ABSTRACT_PUBMED_16765046}}
==About this Structure==
==About this Structure==
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2GU8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GU8 OCA].
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[[2gu8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GU8 OCA].
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==See Also==
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*[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16765046</ref><references group="xtra"/>
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<ref group="xtra">PMID:016765046</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Pka]]
[[Category: Pka]]
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[[Category: Signaling protein]]
[[Category: Ternary complex]]
[[Category: Ternary complex]]
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[[Category: Transferase-inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:01:04 2009''
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Revision as of 11:59, 7 January 2013

Template:STRUCTURE 2gu8

Contents

Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies

Template:ABSTRACT PUBMED 16765046

About this Structure

2gu8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lin X, Murray JM, Rico AC, Wang MX, Chu DT, Zhou Y, Del Rosario M, Kaufman S, Ma S, Fang E, Crawford K, Jefferson AB. Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4163-8. Epub 2006 Jun 9. PMID:16765046 doi:10.1016/j.bmcl.2006.05.092

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