2gu8

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Revision as of 11:59, 7 January 2013

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Template:STRUCTURE 2gu8

Contents 1 Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies 2 About this Structure 3 See Also 4 Reference

Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies

Template:ABSTRACT PUBMED 16765046

About this Structure

2gu8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• CAMP-dependent protein kinase

Reference

• Lin X, Murray JM, Rico AC, Wang MX, Chu DT, Zhou Y, Del Rosario M, Kaufman S, Ma S, Fang E, Crawford K, Jefferson AB. Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4163-8. Epub 2006 Jun 9. PMID:16765046 doi:10.1016/j.bmcl.2006.05.092