This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2itk
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2itk.png|left|200px]] | [[Image:2itk.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2itk", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2itk| PDB=2itk | SCENE= }} | {{STRUCTURE_2itk| PDB=2itk | SCENE= }} | ||
===human Pin1 bound to D-PEPTIDE=== | ===human Pin1 bound to D-PEPTIDE=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17518432}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17518432 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17518432}} | {{ABSTRACT_PUBMED_17518432}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2itk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITK OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017518432</ref><ref group="xtra">PMID:021980916</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Peptidylprolyl isomerase]] | [[Category: Peptidylprolyl isomerase]] | ||
| Line 29: | Line 17: | ||
[[Category: Zhang, Y.]] | [[Category: Zhang, Y.]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
| + | [[Category: Isomerase-isomerase inhibitor complex]] | ||
[[Category: Pin1]] | [[Category: Pin1]] | ||
[[Category: Ww domain]] | [[Category: Ww domain]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:25:40 2009'' | ||
Revision as of 12:02, 7 January 2013
human Pin1 bound to D-PEPTIDE
Template:ABSTRACT PUBMED 17518432
About this Structure
2itk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lucke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. ACS Chem Biol. 2007 May 22;2(5):320-8. PMID:17518432 doi:http://dx.doi.org/10.1021/cb7000044
- Xu GG, Zhang Y, Mercedes-Camacho AY, Etzkorn FA. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. Biochemistry. 2011 Nov 8;50(44):9545-50. Epub 2011 Oct 18. PMID:21980916 doi:10.1021/bi201055c
