This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2i0a
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2i0a.png|left|200px]] | [[Image:2i0a.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2i0a", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2i0a| PDB=2i0a | SCENE= }} | {{STRUCTURE_2i0a| PDB=2i0a | SCENE= }} | ||
===Crystal Structure of KB-19 complexed with wild type HIV-1 protease=== | ===Crystal Structure of KB-19 complexed with wild type HIV-1 protease=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17149864}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17149864 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17149864}} | {{ABSTRACT_PUBMED_17149864}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2i0a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0A OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017149864</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Ali, A.]] | [[Category: Ali, A.]] | ||
| Line 34: | Line 22: | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Hiv-1 protease]] | [[Category: Hiv-1 protease]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:49:46 2009'' | ||
Revision as of 13:18, 7 January 2013
Crystal Structure of KB-19 complexed with wild type HIV-1 protease
Template:ABSTRACT PUBMED 17149864
About this Structure
2i0a is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Ali A, Reddy GS, Cao H, Anjum SG, Nalam MN, Schiffer CA, Rana TM. Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands. J Med Chem. 2006 Dec 14;49(25):7342-56. PMID:17149864 doi:10.1021/jm060666p
