2hb3

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[[Image:2hb3.png|left|200px]]
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{{STRUCTURE_2hb3| PDB=2hb3 | SCENE= }}
{{STRUCTURE_2hb3| PDB=2hb3 | SCENE= }}
===Wild-type HIV-1 Protease in complex with potent inhibitor GRL06579===
===Wild-type HIV-1 Protease in complex with potent inhibitor GRL06579===
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{{ABSTRACT_PUBMED_16913714}}
{{ABSTRACT_PUBMED_16913714}}
==About this Structure==
==About this Structure==
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2HB3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HB3 OCA].
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[[2hb3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HB3 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16913714</ref><references group="xtra"/>
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<ref group="xtra">PMID:016913714</ref><references group="xtra"/>
[[Category: Chymosin]]
[[Category: Chymosin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Weber, I T.]]
[[Category: Weber, I T.]]
[[Category: Active-site cavity protease inhibitor catalytic aspartic acid]]
[[Category: Active-site cavity protease inhibitor catalytic aspartic acid]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:39:07 2009''
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Revision as of 14:26, 7 January 2013

Template:STRUCTURE 2hb3

Wild-type HIV-1 Protease in complex with potent inhibitor GRL06579

Template:ABSTRACT PUBMED 16913714

About this Structure

2hb3 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ghosh AK, Sridhar PR, Leshchenko S, Hussain AK, Li J, Kovalevsky AY, Walters DE, Wedekind JE, Grum-Tokars V, Das D, Koh Y, Maeda K, Gatanaga H, Weber IT, Mitsuya H. Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance. J Med Chem. 2006 Aug 24;49(17):5252-61. PMID:16913714 doi:10.1021/jm060561m

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