2hb3
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | {{Seed}} | ||
[[Image:2hb3.png|left|200px]] | [[Image:2hb3.png|left|200px]] | ||
- | <!-- | ||
- | The line below this paragraph, containing "STRUCTURE_2hb3", creates the "Structure Box" on the page. | ||
- | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
- | or leave the SCENE parameter empty for the default display. | ||
- | --> | ||
{{STRUCTURE_2hb3| PDB=2hb3 | SCENE= }} | {{STRUCTURE_2hb3| PDB=2hb3 | SCENE= }} | ||
===Wild-type HIV-1 Protease in complex with potent inhibitor GRL06579=== | ===Wild-type HIV-1 Protease in complex with potent inhibitor GRL06579=== | ||
- | |||
- | <!-- | ||
- | The line below this paragraph, {{ABSTRACT_PUBMED_16913714}}, adds the Publication Abstract to the page | ||
- | (as it appears on PubMed at http://www.pubmed.gov), where 16913714 is the PubMed ID number. | ||
- | --> | ||
{{ABSTRACT_PUBMED_16913714}} | {{ABSTRACT_PUBMED_16913714}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2hb3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HB3 OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016913714</ref><references group="xtra"/> |
[[Category: Chymosin]] | [[Category: Chymosin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
Line 29: | Line 17: | ||
[[Category: Weber, I T.]] | [[Category: Weber, I T.]] | ||
[[Category: Active-site cavity protease inhibitor catalytic aspartic acid]] | [[Category: Active-site cavity protease inhibitor catalytic aspartic acid]] | ||
- | + | [[Category: Hydrolase]] | |
- | + |
Revision as of 14:26, 7 January 2013
Wild-type HIV-1 Protease in complex with potent inhibitor GRL06579
Template:ABSTRACT PUBMED 16913714
About this Structure
2hb3 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Ghosh AK, Sridhar PR, Leshchenko S, Hussain AK, Li J, Kovalevsky AY, Walters DE, Wedekind JE, Grum-Tokars V, Das D, Koh Y, Maeda K, Gatanaga H, Weber IT, Mitsuya H. Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance. J Med Chem. 2006 Aug 24;49(17):5252-61. PMID:16913714 doi:10.1021/jm060561m