2f81

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[[Image:2f81.png|left|200px]]
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{{STRUCTURE_2f81| PDB=2f81 | SCENE= }}
{{STRUCTURE_2f81| PDB=2f81 | SCENE= }}
===HIV-1 Protease mutant L90M complexed with inhibitor TMC114===
===HIV-1 Protease mutant L90M complexed with inhibitor TMC114===
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{{ABSTRACT_PUBMED_16480273}}
{{ABSTRACT_PUBMED_16480273}}
==About this Structure==
==About this Structure==
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2F81 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F81 OCA].
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[[2f81]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F81 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16480273</ref><references group="xtra"/>
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<ref group="xtra">PMID:016480273</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Weber, I T.]]
[[Category: Weber, I T.]]
[[Category: Hiv-1 protease-inhibitor complex]]
[[Category: Hiv-1 protease-inhibitor complex]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:44:16 2009''
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Revision as of 14:36, 7 January 2013

Template:STRUCTURE 2f81

HIV-1 Protease mutant L90M complexed with inhibitor TMC114

Template:ABSTRACT PUBMED 16480273

About this Structure

2f81 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Kovalevsky AY, Tie Y, Liu F, Boross PI, Wang YF, Leshchenko S, Ghosh AK, Harrison RW, Weber IT. Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M. J Med Chem. 2006 Feb 23;49(4):1379-87. PMID:16480273 doi:http://dx.doi.org/10.1021/jm050943c

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