2pjy
From Proteopedia
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[[Image:2pjy.png|left|200px]] | [[Image:2pjy.png|left|200px]] | ||
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{{STRUCTURE_2pjy| PDB=2pjy | SCENE= }} | {{STRUCTURE_2pjy| PDB=2pjy | SCENE= }} | ||
===Structural basis for cooperative assembly of the TGF-beta signaling complex=== | ===Structural basis for cooperative assembly of the TGF-beta signaling complex=== | ||
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| - | (as it appears on PubMed at http://www.pubmed.gov), where 18243111 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_18243111}} | {{ABSTRACT_PUBMED_18243111}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Arrhythmogenic right ventricular dysplasia 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190230 190230]], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Esophageal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 1B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 2B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2pjy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJY OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018243111</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein serine/threonine kinase]] | [[Category: Receptor protein serine/threonine kinase]] | ||
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[[Category: Ternary complex]] | [[Category: Ternary complex]] | ||
[[Category: Three finger toxin]] | [[Category: Three finger toxin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 08:56:08 2010'' | ||
Revision as of 14:43, 7 January 2013
Structural basis for cooperative assembly of the TGF-beta signaling complex
Template:ABSTRACT PUBMED 18243111
About this Structure
2pjy is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, Taylor AB, Schwarz PM, Wrana JL, Hinck AP. Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol Cell. 2008 Feb 1;29(2):157-68. PMID:18243111 doi:10.1016/j.molcel.2007.11.039
