2o2k
From Proteopedia
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===Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N=== | ===Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Methylcobalamin deficiency, cblG type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]], Cleft lip/palate, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]], Down syndrome, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]], Neural tube defects, folate-sensitive, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2o2k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2K OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017288554</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Methionine synthase]] | [[Category: Methionine synthase]] | ||
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[[Category: Beta-meander region]] | [[Category: Beta-meander region]] | ||
[[Category: C-shaped]] | [[Category: C-shaped]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Twisted anti-parallel beta sheet]] | [[Category: Twisted anti-parallel beta sheet]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:49:22 2009'' | ||
Revision as of 15:10, 7 January 2013
Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N
Template:ABSTRACT PUBMED 17288554
About this Structure
2o2k is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wolthers KR, Toogood HS, Jowitt TA, Marshall KR, Leys D, Scrutton NS. Crystal structure and solution characterization of the activation domain of human methionine synthase. FEBS J. 2007 Feb;274(3):738-50. PMID:17288554 doi:10.1111/j.1742-4658.2006.05618.x
