2ooh
From Proteopedia
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[[Image:2ooh.png|left|200px]] | [[Image:2ooh.png|left|200px]] | ||
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{{STRUCTURE_2ooh| PDB=2ooh | SCENE= }} | {{STRUCTURE_2ooh| PDB=2ooh | SCENE= }} | ||
===Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11=== | ===Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11=== | ||
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{{ABSTRACT_PUBMED_17526494}} | {{ABSTRACT_PUBMED_17526494}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Persistent Mullerian duct syndrome, type I OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600957 600957]], Rheumatoid arthritis, systemic juvenile, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=153620 153620]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2ooh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OOH OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017526494</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylpyruvate tautomerase]] | [[Category: Phenylpyruvate tautomerase]] | ||
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[[Category: Alternative ligand-binding mode]] | [[Category: Alternative ligand-binding mode]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:26:30 2009'' | ||
Revision as of 15:13, 7 January 2013
Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11
Template:ABSTRACT PUBMED 17526494
About this Structure
2ooh is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Crichlow GV, Cheng KF, Dabideen D, Ochani M, Aljabari B, Pavlov VA, Miller EJ, Lolis E, Al-Abed Y. Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor. J Biol Chem. 2007 Aug 10;282(32):23089-95. Epub 2007 May 25. PMID:17526494 doi:http://dx.doi.org/10.1074/jbc.M701825200
