3clx

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[[Image:3clx.png|left|200px]]
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{{STRUCTURE_3clx| PDB=3clx | SCENE= }}
{{STRUCTURE_3clx| PDB=3clx | SCENE= }}
===Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac005===
===Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac005===
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{{ABSTRACT_PUBMED_18851976}}
{{ABSTRACT_PUBMED_18851976}}
==About this Structure==
==About this Structure==
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3CLX is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CLX OCA].
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[[3clx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CLX OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:18851976</ref><references group="xtra"/>
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<ref group="xtra">PMID:018851976</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cossu, F.]]
[[Category: Cossu, F.]]
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[[Category: Milani, M.]]
[[Category: Milani, M.]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
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[[Category: Cytoplasm]]
 
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
 
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
[[Category: Thiol protease inhibitor]]
[[Category: Thiol protease inhibitor]]
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[[Category: Ubl conjugation]]
 
[[Category: Ubl conjugation pathway]]
[[Category: Ubl conjugation pathway]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:30:38 2009''
 

Revision as of 18:08, 7 January 2013

Template:STRUCTURE 3clx

Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac005

Template:ABSTRACT PUBMED 18851976

About this Structure

3clx is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mastrangelo E, Cossu F, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Drago C, Seneci P, Scolastico C, Rizzo V, Bolognesi M. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles. J Mol Biol. 2008 Dec 19;384(3):673-89. Epub 2008 Oct 7. PMID:18851976 doi:10.1016/j.jmb.2008.09.064

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