2tct

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Revision as of 18:11, 7 January 2013

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Template:STRUCTURE 2tct

THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE

Template:ABSTRACT PUBMED 7707374

About this Structure

2tct is a 1 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1tct. Full crystallographic information is available from OCA.

Reference

• Kisker C, Hinrichs W, Tovar K, Hillen W, Saenger W. The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance. J Mol Biol. 1995 Mar 24;247(2):260-80. PMID:7707374
• Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W. Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline. J Mol Biol. 1999 Jan 15;285(2):455-61. PMID:9878420 doi:10.1006/jmbi.1998.2290