3cqw
From Proteopedia
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Revision as of 18:17, 7 January 2013
Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor
Template:ABSTRACT PUBMED 18456494
About this Structure
3cqw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lippa B, Pan G, Corbett M, Li C, Kauffman GS, Pandit J, Robinson S, Wei L, Kozina E, Marr ES, Borzillo G, Knauth E, Barbacci-Tobin EG, Vincent P, Troutman M, Baker D, Rajamohan F, Kakar S, Clark T, Morris J. Synthesis and structure based optimization of novel Akt inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3359-63. Epub 2008 Apr 15. PMID:18456494 doi:10.1016/j.bmcl.2008.04.034
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Pandit, J. | Apoptosis | Atp-binding | Carbohydrate metabolism | Glucose metabolism | Glycogen biosynthesis | Glycogen metabolism | Kinase | Membrane | Nucleotide-binding | Nucleus | Phosphoprotein | Serine/threonine-protein kinase | Sugar transport | Transferase | Translation regulation | Transport | Wnt signaling pathway
