2xcf
From Proteopedia
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m (Protected "2xcf" [edit=sysop:move=sysop]) |
Revision as of 18:30, 7 January 2013
CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
Template:ABSTRACT PUBMED 20493689
About this Structure
2xcf is a 4 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Li X, Zhang YK, Liu Y, Ding CZ, Li Q, Zhou Y, Plattner JJ, Baker SJ, Qian X, Fan D, Liao L, Ni ZJ, White GV, Mordaunt JE, Lazarides LX, Slater MJ, Jarvest RL, Thommes P, Ellis M, Edge CM, Hubbard JA, Somers D, Rowland P, Nassau P, McDowell B, Skarzynski TJ, Kazmierski WM, Grimes RM, Wright LL, Smith GK, Zou W, Wright J, Pennicott LE. Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3550-6. Epub 2010 May 20. PMID:20493689 doi:10.1016/j.bmcl.2010.04.129
Categories: Hepatitis c virus | Baker, S J. | Ding, C Z. | Edge, C M. | Ellis, M. | Fan, D. | Grimes, R M. | Hubbard, J A. | Jarvest, R L. | Kazmierski, W M. | Lazarides, L X. | Li, Q. | Li, X. | Liao, L. | Liu, Y. | Mcdowell, B. | Mordaunt, J E. | Nassau, P. | Ni, Z J. | Pennicott, L E. | Plattner, J J. | Qian, X. | Rowland, P. | Skarzynski, T J. | Slater, M J. | Smith, G K. | Somers, D O. | Thommes, P. | White, G V. | Wright, J. | Wright, L L. | Zhang, Y K. | Zhou, Y. | Zou, W. | Boronate inhibitor | Hydrolase | Protease | Viral reproduction
