3cas
From Proteopedia
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===Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione=== | ===Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione=== | ||
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{{ABSTRACT_PUBMED_19075558}} | {{ABSTRACT_PUBMED_19075558}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3cas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAS OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019075558</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Breton, R]] | [[Category: Breton, R]] | ||
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[[Category: Androstenedione]] | [[Category: Androstenedione]] | ||
[[Category: Bile acid catabolism]] | [[Category: Bile acid catabolism]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Lipid metabolism]] | [[Category: Lipid metabolism]] | ||
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[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
[[Category: Substrate inhibition]] | [[Category: Substrate inhibition]] | ||
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Revision as of 19:11, 7 January 2013
Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione
Template:ABSTRACT PUBMED 19075558
About this Structure
3cas is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Faucher F, Cantin L, Luu-The V, Labrie F, Breton R. Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Biochemistry. 2008 Dec 23;47(51):13537-46. PMID:19075558 doi:10.1021/bi801276h
