This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2qcn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2qcn.png|left|200px]] | [[Image:2qcn.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2qcn", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2qcn| PDB=2qcn | SCENE= }} | {{STRUCTURE_2qcn| PDB=2qcn | SCENE= }} | ||
===Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP=== | ===Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18184586}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18184586 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18184586}} | {{ABSTRACT_PUBMED_18184586}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Oroticaciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=258900 258900]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2qcn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCN OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphoribosyltransferase|Phosphoribosyltransferase]] | ||
| + | *[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018184586</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Orotidine-5'-phosphate decarboxylase]] | [[Category: Orotidine-5'-phosphate decarboxylase]] | ||
[[Category: Rudolph, M.]] | [[Category: Rudolph, M.]] | ||
[[Category: Wittmann, J.]] | [[Category: Wittmann, J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Catalytic proficiency]] | [[Category: Catalytic proficiency]] | ||
[[Category: Decarboxylase]] | [[Category: Decarboxylase]] | ||
| Line 38: | Line 26: | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Multifunctional enzyme]] | [[Category: Multifunctional enzyme]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Pyrimidine biosynthesis]] | [[Category: Pyrimidine biosynthesis]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Ump synthase]] | [[Category: Ump synthase]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:05:41 2009'' | ||
Revision as of 19:27, 7 January 2013
Contents |
Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP
Template:ABSTRACT PUBMED 18184586
About this Structure
2qcn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wittmann JG, Heinrich D, Gasow K, Frey A, Diederichsen U, Rudolph MG. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure. 2008 Jan;16(1):82-92. PMID:18184586 doi:http://dx.doi.org/10.1016/j.str.2007.10.020
