3db8
From Proteopedia
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===Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041=== | ===Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3db8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB8 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018790636</ref><references group="xtra"/> |
[[Category: Danio rerio]] | [[Category: Danio rerio]] | ||
[[Category: Polo kinase]] | [[Category: Polo kinase]] | ||
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[[Category: Small-molecule inhibitor]] | [[Category: Small-molecule inhibitor]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 19:31, 7 January 2013
Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041
Template:ABSTRACT PUBMED 18790636
About this Structure
3db8 is a 1 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.
Reference
- Hanan EJ, Fucini RV, Romanowski MJ, Elling RA, Lew W, Purkey HE, VanderPorten EC, Yang W. Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9. Epub 2008 Aug 29. PMID:18790636 doi:10.1016/j.bmcl.2008.08.091
