2z8c
From Proteopedia
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{{STRUCTURE_2z8c| PDB=2z8c | SCENE= }} | {{STRUCTURE_2z8c| PDB=2z8c | SCENE= }} | ||
===Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid=== | ===Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid=== | ||
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{{ABSTRACT_PUBMED_18767165}} | {{ABSTRACT_PUBMED_18767165}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Coronary artery disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147545 147545]], Diabetes mellitus, noninsulin-dependent OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147545 147545]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2z8c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8C OCA]. | |
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| + | ==See Also== | ||
| + | *[[Insulin receptor|Insulin receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018767165</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Katayama, N.]] | [[Category: Katayama, N.]] | ||
[[Category: Kurihara, H.]] | [[Category: Kurihara, H.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Carbohydrate metabolism]] | [[Category: Carbohydrate metabolism]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Transducer]] | [[Category: Transducer]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:08:10 2009'' | ||
Revision as of 19:31, 7 January 2013
Contents |
Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid
Template:ABSTRACT PUBMED 18767165
About this Structure
2z8c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Katayama N, Orita M, Yamaguchi T, Hisamichi H, Kuromitsu S, Kurihara H, Sakashita H, Matsumoto Y, Fujita S, Niimi T. Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors. Proteins. 2008 Sep 2;73(4):795-801. PMID:18767165 doi:10.1002/prot.22207
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Katayama, N. | Kurihara, H. | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphorylation | Receptor | Transducer | Transferase | Transmembrane | Tyrosine-protein kinase
