3cot

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[[Image:3cot.png|left|200px]]
[[Image:3cot.png|left|200px]]
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{{STRUCTURE_3cot| PDB=3cot | SCENE= }}
{{STRUCTURE_3cot| PDB=3cot | SCENE= }}
===Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.===
===Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.===
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{{ABSTRACT_PUBMED_18407998}}
{{ABSTRACT_PUBMED_18407998}}
==About this Structure==
==About this Structure==
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3COT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COT OCA].
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[[3cot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COT OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:18407998</ref><references group="xtra"/>
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<ref group="xtra">PMID:018407998</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Christianson, D W.]]
[[Category: Christianson, D W.]]
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[[Category: 5beta reductase]]
[[Category: 5beta reductase]]
[[Category: Bile acid catabolism]]
[[Category: Bile acid catabolism]]
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[[Category: Cytoplasm]]
 
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: E120]]
[[Category: E120]]
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[[Category: Steroid c-c double bond reduction]]
[[Category: Steroid c-c double bond reduction]]
[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:11:33 2009''
 

Revision as of 19:50, 7 January 2013

Template:STRUCTURE 3cot

Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.

Template:ABSTRACT PUBMED 18407998

About this Structure

3cot is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Di Costanzo L, Drury JE, Penning TM, Christianson DW. Crystal structure of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and implications for substrate binding and catalysis. J Biol Chem. 2008 Jun 13;283(24):16830-9. Epub 2008 Apr 11. PMID:18407998 doi:http://dx.doi.org/10.1074/jbc.M801778200

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