3cot

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Revision as of 19:50, 7 January 2013

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Template:STRUCTURE 3cot

Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.

Template:ABSTRACT PUBMED 18407998

About this Structure

3cot is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Di Costanzo L, Drury JE, Penning TM, Christianson DW. Crystal structure of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and implications for substrate binding and catalysis. J Biol Chem. 2008 Jun 13;283(24):16830-9. Epub 2008 Apr 11. PMID:18407998 doi:http://dx.doi.org/10.1074/jbc.M801778200