2wj2
From Proteopedia
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3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH 7-PHENYL-1-(5-(PYRIDIN-2-YL)OXAZOL-2-YL)HEPTAN-1-ONE, AN ALPHA-KETOOXAZOLE
Template:ABSTRACT PUBMED 19722626
About this Structure
2wj2 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Mileni M, Garfunkle J, DeMartino JK, Cravatt BF, Boger DL, Stevens RC. Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures. J Am Chem Soc. 2009 Aug 5;131(30):10497-506. PMID:19722626 doi:10.1021/ja902694n
Categories: Amidase | Rattus norvegicus | Boger, D L. | Cravatt, B F. | Demartino, J K. | Garfunkle, J. | Mileni, M. | Stevens, R C. | Alpha-ketooxazole | Covalent reversible inhibitor | Endoplasmic reticulum | Fatty acid amide hydrolase | Golgi apparatus | Hydrolase | Membrane | Monotopic membrane protein | Phosphoprotein | Transmembrane