3bps
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3bps| PDB=3bps | SCENE= }} | {{STRUCTURE_3bps| PDB=3bps | SCENE= }} | ||
===PCSK9:EGF-A complex=== | ===PCSK9:EGF-A complex=== | ||
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{{ABSTRACT_PUBMED_18250299}} | {{ABSTRACT_PUBMED_18250299}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606945 606945]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3bps]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPS OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018250299</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kwon, H J.]] | [[Category: Kwon, H J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Autocatalytic cleavage]] | [[Category: Autocatalytic cleavage]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cholesterol metabolism]] | [[Category: Cholesterol metabolism]] | ||
[[Category: Coated pit]] | [[Category: Coated pit]] | ||
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[[Category: Host-virus interaction]] | [[Category: Host-virus interaction]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-lipid transport complex]] |
[[Category: Ldl receptor]] | [[Category: Ldl receptor]] | ||
[[Category: Lipid metabolism]] | [[Category: Lipid metabolism]] | ||
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[[Category: Pcsk9]] | [[Category: Pcsk9]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
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[[Category: Transport]] | [[Category: Transport]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:33:47 2009'' | ||
Revision as of 20:52, 7 January 2013
PCSK9:EGF-A complex
Template:ABSTRACT PUBMED 18250299
About this Structure
3bps is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kwon HJ, Lagace TA, McNutt MC, Horton JD, Deisenhofer J. Molecular basis for LDL receptor recognition by PCSK9. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1820-5. Epub 2008 Feb 4. PMID:18250299
Categories: Homo sapiens | Kwon, H J. | Autocatalytic cleavage | Cholesterol metabolism | Coated pit | Disease mutation | Egf-like domain | Endocytosis | Glycoprotein | Host-virus interaction | Hydrolase | Hydrolase-lipid transport complex | Ldl receptor | Lipid metabolism | Lipid transport | Membrane | Pcsk9 | Phosphoprotein | Protease | Secreted | Serine protease | Steroid metabolism | Transmembrane | Transport | Zymogen
