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2r3v

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{{Seed}}
 
[[Image:2r3v.png|left|200px]]
[[Image:2r3v.png|left|200px]]
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{{STRUCTURE_2r3v| PDB=2r3v | SCENE= }}
{{STRUCTURE_2r3v| PDB=2r3v | SCENE= }}
===The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism===
===The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism===
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{{ABSTRACT_PUBMED_18302342}}
{{ABSTRACT_PUBMED_18302342}}
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==Disease==
 
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Known disease associated with this structure: Hyper-IgD syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=251170 251170]], Mevalonic aciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=251170 251170]]
 
==About this Structure==
==About this Structure==
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2R3V is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3V OCA].
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[[2r3v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3V OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:18302342</ref><references group="xtra"/>
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<ref group="xtra">PMID:018302342</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mevalonate kinase]]
[[Category: Mevalonate kinase]]
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[[Category: Cataract]]
[[Category: Cataract]]
[[Category: Cholesterol biosynthesis]]
[[Category: Cholesterol biosynthesis]]
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[[Category: Cytoplasm]]
 
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Farnesyl thiodiphophate]]
[[Category: Farnesyl thiodiphophate]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Peroxisome]]
[[Category: Peroxisome]]
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[[Category: Polymorphism]]
 
[[Category: Steroid biosynthesis]]
[[Category: Steroid biosynthesis]]
[[Category: Sterol biosynthesis]]
[[Category: Sterol biosynthesis]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:44:17 2009''
 

Revision as of 20:59, 7 January 2013

Image:2r3v.png

Template:STRUCTURE 2r3v

The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism

Template:ABSTRACT PUBMED 18302342

About this Structure

2r3v is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Fu Z, Voynova NE, Herdendorf TJ, Miziorko HM, Kim JJ. Biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism. Biochemistry. 2008 Mar 25;47(12):3715-24. Epub 2008 Feb 27. PMID:18302342 doi:10.1021/bi7024386

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