2r3v
From Proteopedia
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{{STRUCTURE_2r3v| PDB=2r3v | SCENE= }} | {{STRUCTURE_2r3v| PDB=2r3v | SCENE= }} | ||
===The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism=== | ===The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism=== | ||
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{{ABSTRACT_PUBMED_18302342}} | {{ABSTRACT_PUBMED_18302342}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hyper-IgD syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=251170 251170]], Mevalonic aciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=251170 251170]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2r3v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3V OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018302342</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mevalonate kinase]] | [[Category: Mevalonate kinase]] | ||
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[[Category: Cataract]] | [[Category: Cataract]] | ||
[[Category: Cholesterol biosynthesis]] | [[Category: Cholesterol biosynthesis]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Farnesyl thiodiphophate]] | [[Category: Farnesyl thiodiphophate]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Peroxisome]] | [[Category: Peroxisome]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Steroid biosynthesis]] | [[Category: Steroid biosynthesis]] | ||
[[Category: Sterol biosynthesis]] | [[Category: Sterol biosynthesis]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 20:59, 7 January 2013
The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism
Template:ABSTRACT PUBMED 18302342
About this Structure
2r3v is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fu Z, Voynova NE, Herdendorf TJ, Miziorko HM, Kim JJ. Biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism. Biochemistry. 2008 Mar 25;47(12):3715-24. Epub 2008 Feb 27. PMID:18302342 doi:10.1021/bi7024386
Categories: Homo sapiens | Mevalonate kinase | Fu, Z. | Kim, J P. | Miziorko, H M. | Voynova, N E. | Atp-binding | Cataract | Cholesterol biosynthesis | Disease mutation | Farnesyl thiodiphophate | Lipid synthesis | Nucleotide-binding | Peroxisome | Steroid biosynthesis | Sterol biosynthesis | Transferase
