2w1i
From Proteopedia
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{{STRUCTURE_2w1i| PDB=2w1i | SCENE= }} | {{STRUCTURE_2w1i| PDB=2w1i | SCENE= }} | ||
===STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR=== | ===STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR=== | ||
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{{ABSTRACT_PUBMED_19143567}} | {{ABSTRACT_PUBMED_19143567}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2w1i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1I OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019143567</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Aurora]] | [[Category: Aurora]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
| - | [[Category: Chromosomal rearrangement]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Sh2 domain]] | [[Category: Sh2 domain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:39:15 2009'' | ||
Revision as of 21:02, 7 January 2013
STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR
Template:ABSTRACT PUBMED 19143567
About this Structure
2w1i is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL, Heathcote M, Maman S, Matthews JE, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Rees DC, Reule M, Tisi D, Williams G, Vinkovic M, Wyatt PG. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. J Med Chem. 2009 Jan 22;52(2):379-88. PMID:19143567 doi:10.1021/jm800984v
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Berdini, V. | Boulstridge, J A. | Brien, M A.O. | Carr, M G. | Cross, D M. | Curry, J. | Devine, L A. | Early, T R. | Fazal, L. | Gill, A L. | Heathcote, M. | Howard, S. | Maman, S. | Matthews, J E. | Mcmenamin, R L. | Navarro, E F. | Rees, D C. | Reilly, M O. | Reule, M. | Tisi, D. | Vinkovic, M. | Williams, G. | Wyatt, P G. | Atp-binding | Aurora | Cancer | Disease mutation | Inhibitor | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Sh2 domain | Transferase | Tyrosine-protein kinase
