3daj

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Revision as of 21:14, 7 January 2013

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Template:STRUCTURE 3daj

Crystal structure of Aurora A complexed with an inhibitor discovered through site-directed dynamic tethering

Template:ABSTRACT PUBMED 18579375

About this Structure

3daj is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

• Cancilla MT, He MM, Viswanathan N, Simmons RL, Taylor M, Fung AD, Cao K, Erlanson DA. Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3978-81. Epub 2008 Jun 10. PMID:18579375 doi:10.1016/j.bmcl.2008.06.011