1xx5
From Proteopedia
(New page: 200px<br /><applet load="1xx5" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xx5, resolution 2.40Å" /> '''Crystal Structure of...) |
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| - | [[Image:1xx5.gif|left|200px]]<br /><applet load="1xx5" size=" | + | [[Image:1xx5.gif|left|200px]]<br /><applet load="1xx5" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1xx5, resolution 2.40Å" /> | caption="1xx5, resolution 2.40Å" /> | ||
'''Crystal Structure of Natrin from Naja atra snake venom'''<br /> | '''Crystal Structure of Natrin from Naja atra snake venom'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Cysteine-rich secretory proteins (CRISPs) are widely distributed in | + | Cysteine-rich secretory proteins (CRISPs) are widely distributed in mammals and snake venoms. They possess apparent homology but varying functions. The structure of CRISPs has remained elusive. Two novel members of the family, natrin and stecrisp, have been purified from Naja atra and Trimeresurus stejnegeri venoms, respectively. Their crystals diffract X-rays to resolution limits of 2.1 and 1.6 angstroms, respectively, and belong to the orthorhombic system with different space groups, unit-cell parameters and numbers of molecules per asymmetric unit. Their structures will contribute a structural basis for further functional studies of this family. |
==About this Structure== | ==About this Structure== | ||
| - | 1XX5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_atra Naja atra] with EOH as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1XX5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_atra Naja atra] with <scene name='pdbligand=EOH:'>EOH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XX5 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Guo, M.]] | [[Category: Guo, M.]] | ||
| - | [[Category: Lou, X | + | [[Category: Lou, X H.]] |
| - | [[Category: Niu, L | + | [[Category: Niu, L W.]] |
[[Category: Shen, B.]] | [[Category: Shen, B.]] | ||
| - | [[Category: Teng, M | + | [[Category: Teng, M K.]] |
[[Category: Wang, J.]] | [[Category: Wang, J.]] | ||
[[Category: EOH]] | [[Category: EOH]] | ||
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[[Category: natrin]] | [[Category: natrin]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:59:31 2008'' |
Revision as of 13:59, 21 February 2008
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Crystal Structure of Natrin from Naja atra snake venom
Overview
Cysteine-rich secretory proteins (CRISPs) are widely distributed in mammals and snake venoms. They possess apparent homology but varying functions. The structure of CRISPs has remained elusive. Two novel members of the family, natrin and stecrisp, have been purified from Naja atra and Trimeresurus stejnegeri venoms, respectively. Their crystals diffract X-rays to resolution limits of 2.1 and 1.6 angstroms, respectively, and belong to the orthorhombic system with different space groups, unit-cell parameters and numbers of molecules per asymmetric unit. Their structures will contribute a structural basis for further functional studies of this family.
About this Structure
1XX5 is a Single protein structure of sequence from Naja atra with as ligand. Full crystallographic information is available from OCA.
Reference
Purification, partial characterization, crystallization and preliminary X-ray diffraction of two cysteine-rich secretory proteins from Naja atra and Trimeresurus stejnegeri venoms., Tu X, Wang J, Guo M, Zheng D, Teng M, Niu L, Liu Q, Huang Q, Hao Q, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1108-11. Epub 2004, May 21. PMID:15159571
Page seeded by OCA on Thu Feb 21 15:59:31 2008
Categories: Naja atra | Single protein | Guo, M. | Lou, X H. | Niu, L W. | Shen, B. | Teng, M K. | Wang, J. | EOH | Crisps | Natrin
