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2qtl
From Proteopedia
(Difference between revisions)
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[[Image:2qtl.png|left|200px]] | [[Image:2qtl.png|left|200px]] | ||
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{{STRUCTURE_2qtl| PDB=2qtl | SCENE= }} | {{STRUCTURE_2qtl| PDB=2qtl | SCENE= }} | ||
===Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase=== | ===Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase=== | ||
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{{ABSTRACT_PUBMED_17892308}} | {{ABSTRACT_PUBMED_17892308}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Homocystinuria-megaloblastic anemia, cbl E type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602568 602568]], Neural tube defects, folate-sensitive, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602568 602568]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2qtl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QTL OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017892308</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Leys, D.]] | [[Category: Leys, D.]] | ||
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[[Category: Flexible hinge region]] | [[Category: Flexible hinge region]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:28:58 2009'' | ||
Revision as of 21:29, 7 January 2013
Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase
Template:ABSTRACT PUBMED 17892308
About this Structure
2qtl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wolthers KR, Lou X, Toogood HS, Leys D, Scrutton NS. Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry. Biochemistry. 2007 Oct 23;46(42):11833-44. Epub 2007 Sep 25. PMID:17892308 doi:10.1021/bi701209p
