2w5z
From Proteopedia
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Revision as of 21:30, 7 January 2013
TERNARY COMPLEX OF THE MIXED LINEAGE LEUKAEMIA (MLL1) SET DOMAIN WITH THE COFACTOR PRODUCT S-ADENOSYLHOMOCYSTEINE AND HISTONE PEPTIDE.
Template:ABSTRACT PUBMED 19187761
About this Structure
2w5z is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Southall SM, Wong PS, Odho Z, Roe SM, Wilson JR. Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks. Mol Cell. 2009 Jan 30;33(2):181-91. PMID:19187761 doi:10.1016/j.molcel.2008.12.029
Categories: Histone-lysine N-methyltransferase | Homo sapiens | Odho, Z. | Roe, S M. | Southall, S M. | Wilson, J R. | Wong, P S. | Apoptosis | Bromodomain | Chromatin regulator | Dna-binding | Histone modification | Kmt2a | Metal-binding | Methyltransferase | Mixed lineage leukaemia | Mll1 | Nucleus | Phosphoprotein | Protein lysine methyltransferase | Proto-oncogene | S-adenosyl-l-methionine | Set domain | Transcription | Transcription regulation | Transferase | Zinc-finger
