2wap

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Image:2wap.png

Template:STRUCTURE 2wap

3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH THE DRUG-LIKE UREA INHIBITOR PF-3845

Template:ABSTRACT PUBMED 19389627

About this Structure

2wap is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, Weerapana E, Sadagopan N, Liimatta M, Smith SE, Lazerwith S, Stiff C, Kamtekar S, Bhattacharya K, Zhang Y, Swaney S, Van Becelaere K, Stevens RC, Cravatt BF. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem Biol. 2009 Apr 24;16(4):411-20. PMID:19389627 doi:10.1016/j.chembiol.2009.02.013

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OCA

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