2vki
From Proteopedia
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{{STRUCTURE_2vki| PDB=2vki | SCENE= }} | {{STRUCTURE_2vki| PDB=2vki | SCENE= }} | ||
===STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT=== | ===STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2vki]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKI OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018347057</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Deak, M.]] | [[Category: Deak, M.]] | ||
[[Category: Komander, D.]] | [[Category: Komander, D.]] | ||
| - | [[Category: 3-phosphoinositide]] | ||
| - | [[Category: Alternative splicing]] | ||
| - | [[Category: Atp-binding]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
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[[Category: Diabetes]] | [[Category: Diabetes]] | ||
| - | [[Category: Kinase]] | ||
| - | [[Category: Membrane]] | ||
| - | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Pdk1]] | ||
| - | [[Category: Phosphorylation]] | ||
| - | [[Category: Pi3-kinase]] | ||
| - | [[Category: Pkb]] | ||
[[Category: Pleckstrin homology]] | [[Category: Pleckstrin homology]] | ||
| - | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 21:40, 7 January 2013
STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT
Template:ABSTRACT PUBMED 18347057
About this Structure
2vki is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bayascas JR, Wullschleger S, Sakamoto K, Garcia-Martinez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol. 2008 May;28(10):3258-72. Epub 2008 Mar 17. PMID:18347057 doi:10.1128/MCB.02032-07
