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2qtw
From Proteopedia
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[[Image:2qtw.png|left|200px]] | [[Image:2qtw.png|left|200px]] | ||
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{{STRUCTURE_2qtw| PDB=2qtw | SCENE= }} | {{STRUCTURE_2qtw| PDB=2qtw | SCENE= }} | ||
===The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain=== | ===The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2qtw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QTW OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017804797</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hampton, E N.]] | [[Category: Hampton, E N.]] | ||
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[[Category: Li, J.]] | [[Category: Li, J.]] | ||
[[Category: Spraggon, G.]] | [[Category: Spraggon, G.]] | ||
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[[Category: Autocatalytic cleavage]] | [[Category: Autocatalytic cleavage]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cholesterol metabolism]] | [[Category: Cholesterol metabolism]] | ||
[[Category: Coronary heart disease]] | [[Category: Coronary heart disease]] | ||
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[[Category: Low density lipoprotein receptor]] | [[Category: Low density lipoprotein receptor]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
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[[Category: Pro-protein convertase]] | [[Category: Pro-protein convertase]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
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[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 22:02, 7 January 2013
The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain
Template:ABSTRACT PUBMED 17804797
About this Structure
2qtw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hampton EN, Knuth MW, Li J, Harris JL, Lesley SA, Spraggon G. The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14604-9. Epub 2007 Sep 5. PMID:17804797
Categories: Homo sapiens | Hampton, E N. | Harris, J L. | Knuth, M W. | Lesley, S A. | Li, J. | Spraggon, G. | Autocatalytic cleavage | Cholesterol metabolism | Coronary heart disease | Disease mutation | Glycoprotein | Hydrolase | Hypercholesterolemia | Lipid metabolism | Low density lipoprotein receptor | Phosphorylation | Pro-protein convertase | Protease | Secreted | Serine protease | Steroid metabolism | Zymogen
