2xng

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[[Image:2xng.png|left|200px]]
[[Image:2xng.png|left|200px]]
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{{STRUCTURE_2xng| PDB=2xng | SCENE= }}
{{STRUCTURE_2xng| PDB=2xng | SCENE= }}
===STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR===
===STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR===
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{{ABSTRACT_PUBMED_20833547}}
{{ABSTRACT_PUBMED_20833547}}
==About this Structure==
==About this Structure==
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2XNG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNG OCA].
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[[2xng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNG OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20833547</ref><references group="xtra"/>
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<ref group="xtra">PMID:020833547</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Ser-thr protein kinase complex]]
[[Category: Ser-thr protein kinase complex]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:44:54 2010''
 

Revision as of 22:27, 7 January 2013

Template:STRUCTURE 2xng

STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR

Template:ABSTRACT PUBMED 20833547

About this Structure

2xng is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bouloc N, Large JM, Kosmopoulou M, Sun C, Faisal A, Matteucci M, Reynisson J, Brown N, Atrash B, Blagg J, McDonald E, Linardopoulos S, Bayliss R, Bavetsias V. Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg Med Chem Lett. 2010 Oct 15;20(20):5988-93. Epub 2010 Aug 21. PMID:20833547 doi:10.1016/j.bmcl.2010.08.091

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